Sickle cell is present from the start of life — you are born with it. It’s hard to know how it will behave in newborns. Infants usually don’t have symptoms in the first few months of life because the fetal hemoglobin produced before birth protects the red blood cells from sickling. A baby may start to have symptoms by six months of age. If you notice any symptoms, be sure to discuss them with your doctor.
Most of the symptoms of sickle cell are related to complications of the disease. Some, such as fatigue, anemia, pain episodes and bone problems, can occur at any age.
Teens and young adults may develop leg ulcers, avascular necrosis (death of bone tissue due to lack of blood supply), acute chest syndrome, and eye damage.
Adults generally have pain crises caused by an injury to a bone, muscle or internal organs.
To manage sickle cell day to day, it’s a good idea to:
Some common symptoms you might have to manage with your sickle cell include:
People with sickle cell, especially infants and children, are more likely to get infections. These infections can include:
When sickled cells get stuck in the blood vessels, it blocks blood flow to the arms and legs. That causes swelling in the hands and feet. Fever may occur as well. This most often happens in children under six years old. About half of children with sickle cell will have this.
Sickle cell can affect the blood vessels in the eyes. That can lead to long-term damage, including loss of vision. The retina is the place where damage usually occurs. The retina is the part of the eye that senses light and sends visual messages to the brain. When it is not working blindness can result.
Sickle cell ulcers are sores that usually start small and then get bigger.
Some ulcers will heal quickly, and others may take longer to heal. Some ulcers come back even after they’ve healed. These ulcers usually start after the age of 10 years.
Sickle cell can block blood vessels leading to the joints. That means that less blood goes to the hips, shoulders, knees and ankles, which might cause damage.
Symptoms include pain and problems with walking and joint movement.
Because of their anemia, children with sickle cell may grow and develop at a slower pace than other children, and they may take longer to reach puberty.
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The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider.